Search below or check out the cancer-associated antigen list, CT antigen list and PTM antigen list. The data can also be downloaded from here.
The cancer antigen atlas (caAtlas) is a comprehensive resource for the selection and prioritization of peptides for immunogenicity testing and cancer immunotherapy development. It was built upon publicly available mass spectrometry (MS)-based human immunopeptidomic datasets from 311 cancer samples covering nine cancer types and 707 non-cancerous samples. Standardized analysis of the 81.6 million MS/MS spectra from these datasets identified 11.3 million peptide-spectrum matches corresponding to 473,288 peptides, including 139,269 modified peptides and 420,702 non-modified peptides. Further analysis of these data provided evidence for tumor specific-presentation of post translationally modified antigens, cancer testis antigens and cancer type-specific tumor associated antigens. caAtlas makes all these data together with annotated MS/MS spectra supporting each individual antigen identification in an easily browsable web portal.
Yi, X., Liao, Y., Wen, B., Li, K., Dou, Y., Savage, S. R., & Zhang, B. (2021). caAtlas: an immunopeptidome atlas of human cancer. Iscience, 24(10). https://doi.org/10.1016/j.isci.2021.103107